BACKGROUND: Some low molecular weight heparins (LMWHs) prolong survival of cancer patients and inhibit experimental metastasis.The underlying mechanisms are still not clear but it has been suggested that LMWHs (at least in part) limit metastasis by preventing cancer cell-induced destruction of the endothelial glycocalyx.METHODOLOGY/PRINCIPAL FINDIN
Abstract Background Gene duplication events play an important role in the evolution and adaptation of organisms.Duplicated genes can arise through different mechanisms, including whole-genome duplications (WGDs).Recently, WGD was suggested to be an important driver of evolution, also in hexapod animals.Results Here, we analyzed 20 high-quality hexa
Phleboviruses are emerging pathogens of public health importance.However, their association with ticks is bl2420pt poorly described, particularly in Africa.Here, adult ticks infesting cattle, goats and sheep were collected in two dryland pastoralist ecosystems of Kenya (Baringo and Kajiado counties) and were screened for infection with phleboviruse
Activity recognition, a key component in pervasive healthcare monitoring, relies on classification algorithms that require labeled data of individuals performing the activity of interest to train accurate models.Labeling data can be performed in a lab setting where an individual enacts the activity under controlled conditions.The ubiquity of mobile
Most bacteria use an indirect pathway to generate aminoacylated glutamine and/or asparagine tRNAs.Clinical isolates of Mycobacterium tuberculosis with increased rates of error in gene translation (mistranslation) involving the indirect tRNA-aminoacylation pathway have increased tolerance to the halloween cookie card first-line antibiotic rifampicin